Helicobacter pylori basso in Hiv +

Da Gex Sab 19 Feb - 16:20

Questo studio brasiliano, ha dimostrato che l' Helicobacter Pylori ha iun tasso di incidenza basso negli Hiv +.
L'Helicobacter Pylori e' un batterio che si insinua nello stomaco e col tempo causa gastrite e ulcera.
Viene eradicato con dosi generose di antibiotico, (e non e' cosi semplice).
Si mischia attraverso la bocca.

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Low prevalence of H. pylori Infection in HIV-Positive Patients in the Northeast of Brazil

: This study conducted in Northeastern Brazil, evaluated the prevalence of H. pylori infection and the presence of gastritis in HIV-infected patients.MethodS: There were included 113 HIV-positive and 141 age-matched HIV-negative patients, who underwent upper gastrointestinal endoscopy for dyspeptic symptoms.

H. pylori status was evaluated by urease test and histology.

Results: : The prevalence of H.

pylori infection was significantly lower (p<0.001) in HIV-infected (37.2%) than in uninfected (75.2%) patients. There were not significant differences between H.

pylori status and gender, age, HIV viral load, antiretroviral therapy and the use of antibiotics. A lower prevalence of H.

pylori was observed among patients with T CD4 cell count below 200/mm3; however, it was not significant. Chronic active antral gastritis was observed in 87.6% of the HIV-infected patients and in 780.4% of the control group (p=0.11).

H. pylori infection was significantly associated with chronic active gastritis in the antrum in both groups, but it was not associated with corpus chronic active gastritis in the HIV-infected patients.CONCLUSION: We demonstrated that the prevalence of H.

pylori was significantly lower in HIV-positive patients compared with HIV-negative ones. However, corpus gastritis was frequently observed in the HIV-positive patients, pointing to different mechanisms than H.

pylori infection in the genesis of the lesion.

Author: Andrea FialhoManuel Braga-NetoEder GuerraAndre FialhoKarinne FernandesJuliana SunChristianne TakedaCicero SilvaDulciene QueirozLucia Braga
Credits/Source: BMC Gastroenterology 2011, 11:13